145th Street is a station on the IRT Lenox Avenue Line of the New York City Subway. Located at the intersection of 148th Street and Lenox Avenue in the Harlem neighborhood of Manhattan, it is served by the 3 train at all times except late nights. 145th Street is one of the few stations in the New York City Subway system that is not open at all times. Between midnight and 6:00 a.m., when the 3 train does not operate, there is a shuttle bus to the 135th Street station, which is served by the 2 train at all times.