During the Second Great War, one was present on Redstone III, and another on Tyrador VIII. The Terran Dominion captured a number of brutalisks—one was held at a bio-weapons lab orbiting Castanar while another two were at Skygeirr Station. During her assault on Skygeirr, Sarah Kerrigan liberated these brutalisks and turned them against their Dominion captors. During the End War, a number of brutalisks were enslaved by Amon and incorporated into his brood. During Amon's attack on the Keystone on Aiur, several brutalisks stood guard over the zerg bases surrounding Hierarch Artanis and his troops.