The Chainsaw Sisters are a class of Chainsaw Ganado. They wielded red chainsaws and wore bandages completely covering their heads. Like the Chainsaw Man, they could be outrun. One of the sisters confronted Ada Wong on her search for a way into the Church. A second sister confronted her near the caves on the other side of the valley. Two other sisters joined together in a camp where they attacked Leon S. Kennedy. However, Leon managed to kill them both.