USS Thermopylae (NCC-74703) was an Intrepid-class cruiser on active duty in Starfleet during the late 24th century. Commissioned ca. 2384, she was deployed to the Starfleet Fifth Fleet during much of her operational lifetime. (Starfleet International: USS Thermopylae) Thermopylae's first commanding officer was Captain Cathey Fuller and her first executive officer was Lieutenant Commander Rose Mattison.