De Mornay's breakout performance came as the call girl that Tom Cruise's character falls in love with in the 1983 film Risky Business. Since that time, she has maintained a stable career, taking a variety of both leading and supporting roles that have resulted in occasional periods of "super-stardom." De Mornay's most successful film to date was The Hand That Rocks the Cradle (1992). In 2004, she guest starred as attorney Hannah Rose for the final few episodes of The Practice, and the following year had a brief role alongside Owen Wilson and Vince Vaughn in Wedding Crashers.