Palatinate-Zweibrücken was the name of a state of the Holy Roman Empire based in the Duchy of Zweibrücken in the southwest of modern Rhineland-Palatinate, Germany. Palatinate-Zweibrücken was partitioned from Palatinate-Simmern and Zweibrücken in 1444 by Stephen for his son Louis I. The new state was granted the County of Veldenz and the Duchy of Zweibrücken. His son and eventual successor Alexander the Lame founded the Alexanderkirche in 1489 in which many future members of the House of Wittelsbach would be buried. Count Palatine Louis II became a proponent of the Reformation, and made possible the Swiss Marburg Colloquy by allowing Protestant theologians to bypass the Archbishopric of Mainz and the Bishoprics of Speyer and Worms.
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