Francois de Lorraine (1506–1525) was the Lord of Lambesc, and a commander in the French army under Francis I of France. He was son of René II, Duke of Lorraine and Phillipa of Guelders. He commanded the Black Band of renegade Landsknechts at the Battle of Pavia, and in the bitter combat that ensued between the Black Band and Frundsberg's Imperial Landsknechts, Lorraine was killed.