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In 1862, she accompanied the army of Ulysses S. Grant during the Battle of Shiloh, where she comforted and ministered to the wounded. Later, she served aboard a pair of military hospital ships on the Mississippi, the City of Memphis and the Hazel Dell. When the war ended in 1865, Safford studied medicine, graduating from the Medical College for Women in New York City four years later. She also studied at the University of Breslaw in Germany, where she performed the first ovariotomy ever done by a woman. Among her publications was Health and Strength Papers for Girls.

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dbr:Mary_J._Safford5.88129e-14
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