The Man-Eating Snake was a huge serpent capable of swallowing a person whole. Its home on Plunder Island was marked with a 'Snake X-ing' sign and a plaque reading: "Massive, Man-Eating Snake. This fantastic reptile is one of Plunder Island's most dangerous and beautiful predators." When Guybrush Threepwood wandered into its home, the snake swallowed him but was forced to throw him back up when he fed it some Syrup of Ipecac.