The 105th Regiment of Foot (Queen's Own Royal Regiment of Highlanders) was a short-lived British line infantry regiment. It was raised in Perthshire by Major-General David Graeme as a two-battalion regiment on 15 October 1760 by converting independent companies. It was named after Charlotte of Mecklenburg-Strelitz, who had been selected as the wife for the future George III of England. The regiment served in Ireland and was disbanded in 1763.