A Zod rune is a high rune which can be socketed into equipment in Diablo II: Lord of Destruction. Zod runes have only two uses, the Breath of the Dying rune word, and making equipment (including ethereal equipment) indestructible. Zod runes remain valuable, however, as they are the rarest rune in the game, and the second rarest item in the game, behind Tyrael's Might.