USS Cassin (DD-372) was a Mahan-class destroyer in the United States Navy before and during World War II. She was the second ship named for Stephen Cassin, an officer in the United States Navy. Cassin was launched at the Philadelphia Navy Yard on 28 October 1935. She was sponsored by Mrs. H. C. Lombard and commissioned 21 August 1936, with Lieutenant Commander A. G. Noble in command.