Anti-Pressure Pills are rather large, oval shaped pills created by Professor Hubert J. Farnsworth. The pills allowed users to survive in high-pressure environments. The pill is a suppository according to a conversation between Philip J. Fry and Professor Farnsworth. Later when the Planet Express crew was going into the depths of the ocean the Professor continually asked them if they had taken their suppository. Amy screamed "YES!! stop asking"
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