Persifor Frazer (August 9, 1736 – April 24, 1792) was an American farmer, soldier, and industrialist, and the founder of one of the most prominent families of Philadelphia, Pennsylvania. Frazer, the son of John and Mary Smith Frazer, was born in Newtown Township, Pennsylvania, not far from Philadelphia. He married Mary "Polly" Taylor on October 2, 1766, and managed a prosperous farm near Brandywine Creek. They raised ten children, many of whom established their own successful businesses and lineages. Grandson Persifor Frazer Smith was a leading brigadier general in the U.S. Army during the Mexican-American War.