I.S.A.A.C. (Intuitive Synthetic Autonomous Assault Commando), played by former UFC Middleweight Champion Rich Franklin, is the first prototype of a confidential "human weapon" program. Once a death-row inmate, he is now a genetically reconstructed, highly trained, deadly assassin whose body and mind have been modified to become a physically regenerative, intellectually superior human being. On the run, I.S.A.A.C. takes Deputy Lindsay Rearden (Tiffani Thiessen; "Beverly Hills, 90210") hostage. Their lives in jeopardy from secret military agents being led by world-renowned robotic engineer Simon Hart (Bruce Greenwood; I, Robot; National Treasure: Book of Secrets), the deputy and I.S.A.A.C. combine forces to expose the military group constructing these super beings.