The Exterminators initial incarnation was a TV pitch and pilot outline as writer Simon Oliver was working in the film industry at the time. After consideration Oliver realized the story wasn't really network material. Oliver then decided to pitch it to a comic book publisher. Luckily a film producer friend of Oliver had become good friends with Karen Berger of Vertigo Comics after they had discussed 100 Bullets. Through this friend the pitch of The Exterminators reached an interested publisher quickly. After some reworking with editor Jon Vankin the project was greenlit and the first issue was released January 2006.