The CRF Mayhem World Championship was one of Championship Rasslin' Federation's titles, the top ranked title on CRF Mayhem brand and created specially for that brand to compete with the CRF Carnage World Championship. It was active from May 2006 until CRF's closure in August 2007, and reactivated in March 2008 with CRF's re-opening and active until all existing top-tier championships were retired in May 2009. A total of thirteen different individuals had reigns with the CRF Mayhem World Championship across a total of fifteen reigns.