Brian Witherspoon (born June 5, 1985) is an American football cornerback and return specialist who is currently a free agent. He was signed by the Jacksonville Jaguars as an undrafted free agent in 2008. He played college football at Stillman. Witherspoon tore his ACL for a second straight season during offseason practices with the Giants, and was waived/injured on May 24. Witherspoon has also played for the Detroit Lions, Carolina Panthers and New York Giants.