See also: Hunting Places and Loot Help __TOC__ The Last Sanctum is the hiding place of some were-beasts. Rumors say they are using this place to cast magic that helps them spreading the were-sickness. It's somehow connected to Ley Lines. When entering the Last Sanctum, you will see this message: After finishing the Grimvale Quest - The Curse Spreads, you can use the death portal to travel between this place and the Edron Lycanthropes Cave. Spoiler ends here.