Radament's Lair is the first quest of Act II. It is activated by talking to Atma. "I don't expect this of you, but if you help me, I would be grateful. In the sewers below our city, there lurks a horrid creature that hungers for human flesh. The creature has killed many, including my son and my husband. If you destroy it, I will reward you. Please be careful though, that beast has taken enough from us already. The sewer entrance is through the trap door just up the street."