In the first episode of the 2003 anime series and third of the 2009 series, Cornello reveals a monstrous leonine chimera as one of the fruits of his false Philosopher's Stone. He sends it to attack Edward but it fails to kill him when it bites into his automail arm, giving him a chance to strike it down. Its corpse is later picked clean by Gluttony. It also serves as the first boss of Fullmetal Alchemist 2: Curse of the Crimson Elixir, being the first scenario wherein Edward can use the alchemical skill to create the lance he uses against it.