Groton was a mute, dimwitted homicidal maniac who lived in Venice Beach, California. He was the assistant of a scientist named Doctor Durae who, unknown to Groton, was in fact the last male heir to the legacy of Frankenstein. He lived in Durae's laboratory, which was situated behind a secret panel at Doctor Durae's Creature Emporium on the boardwalk. Durae was attempting to develop a serum that would cure various physical and mental abnormalities through the study of blood. He used an early version of the serum to temporarily keep Groton’s homicidal rages in check. But Durae also required Groton's savage quirks, and would often deny him the serum whenever he needed to rely upon the brute's bloodlust.
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