Joseph VI Audo was born in 1790 in Alqosh and in 1814 he became monk of the monastery of Rabban Hormizd. He was ordained priest in 1818 and consecrated bishop of Mosul on the March 25, 1825 by the patriarchal administrator Augustine Hindi in Amid. From 1830 to 1847 he served as metropolitan bishop of Amadiyah. After the resignation of patriarch Mar Nicholas I Zaya he was elected Patriarch of the Chaldean Church on July 28, 1847 and confirmed by the pope on September 11, 1848. He died in Mosul on the March 14, 1878.