There are four variations of Colmillos based on HP levels, ranging from 800, 1000, 1200 and 3000. As wolves, Colmillos run very fast and are able to chase down Leon. Their main attack is to pounce and try to rip out Leon's jugular vein. This attack does massive damage and the player has to shake the control stick to throw them off. They sometimes pause and growl before attacking giving the player a chance to attack or flee. They also may spawn Plaga like whips from their bodies. They can use these whips to attack the player.