Progenitor takes place after the events of Conqueror. It describes how the first settlers arrived on Acheron. After 110 years of cryosleep, the humans are awakened when the ship's AI finds a suitable planet for settling, Acheron. Many of the humans are unable to survive this extended period of cryosleep and succumb to cryoshock within hours of waking. Others have fallen into a coma and cannot be woken. The ship's AI converts these humans into Titanborn but they still don't wake. Anicetus, the first Titan, detaches from the ship and begins the terraforming process on the surface.