Melanie Ruthers is a character in Mana Khemia: Alchemists of Al-Revis. Mysterious teacher of Al-Revis Acedamy. She offers a job involving 30,000 cole for someone to go deep sleep. During the first summer break Vayne and co come to infirmary during night as Flay claims there are pools of blood in the infirmary. As Vayne and co try to switch on the light to see whether the pool is a pool of blood or not, Miss Melanie asks them to sniff the "perfume" before doing so which causes them to fall asleep and allows her to clean the mess.