All forms of abilities do not work on Isaac and he is immune to their effects. This means that he cannot be attacked with an ability, shielded or even healed. For this reason, his heart condition has to be treated through a series of surgeries. Telepaths cannot hear or manipulate his thoughts, and clairvoyants would be unable to locate him. He would not be affected by eclipses caused by other abilities, but would be affected by natural ones, and this would be the only time that he could lose the immunity. He would also reflexively see anyone hidden by invisibility or induced unnoticability, and he would not see an illusion. Neither can his abilities be mimicked or copied in any way. This ability is completely reflexive, and cannot be controlled, blocked, removed or suppressed. Isaac can't