Paine was the head football coach at Baylor University in 1913. His record there stands at 4–4–2. From 1917 to 1918, he served as the head coach at the University of Arkansas, posting a 8–3–1 record. In 1920, he served as the coach at Iowa State University posting a 4–4 record. Paine was the quarterback for Amos Alonzo Stagg at the University of Chicago in 1911 and captain of the Basketball team. Paine was an assistant to Stagg at Chicago. Paine graduated from Rush Medical School and was the head of the campus infirmary at Iowa State as well as the football coach. Paine was on the national board of the YMCA, served LA County Hospital for 30 years and was a physician in Glendale California. Paine was an honored alumni of the University of Chicago and headed the Big Ten Club of Southern Cali