Isaac Byrd II (born November 16, 1974 in St. Louis, Missouri) is a former professional American football wide receiver in the National Football League for the Tennessee Titans and Carolina Panthers. He played college football at the University of Kansas. He was heavily sought after by professional baseball teams and was the 24th round draft pick of the San Diego Padres. However, Isaac decided to attend the University of Kansas on a full-ride scholarship to further his career in both football and baseball and to continue his education.