The Omega Program eventually borne its destructive fruit in the form of psionic-based weapons, namely the Psionic Decimator, used by the Imperial military during the war, much to the horror of those encountering them during the War of the Three Powers. Shiro Sanitarium was later destroyed after the war by one of the program's scions, Yuriko Omega, costing many inside the facility their lives - including Shimada and Yuriko's sister, Izumi.