The cerebrate was part of Daggoth's Renegade Swarm after the death of the first Overmind. During the Brood War, Sarah Kerrigan seized control of the cerebrate by severing its ties to the Second Overmind. She immediately used it to quell the disruption to her Tarsonis hive clusters caused by the psi disrupter. Kerrigan secured the aid of Raynor's Raiders and Emperor Arcturus Mengsk against the UED Expeditionary Fleet. The cerebrate took control of Braxis zerg liberated by Dominion psi emitters and used them to destroy the psi disrupter. Later, it helped raid the Kel-Morian Combine alongside protoss Praetor Fenix. The Combine's resources were needed for the coming assault on UED-held Korhal. Kerrigan ordered the cerebrate to infest as many command centers as possible.