The Blood-Rune is a rune used for many high level spells. These are hard to obtain, and therefore have a street price of around 1000-1500 coins each. These runes are used for the Wave spells and God Spells. Some good ways to collect these include thieving the blood rune chests in Ardougne's Chaos Druid Tower's ogre dungeon, pickpocketing heroes and killing monsters. Below is a table of spells that use blood runes.
Graph IRI | Count |
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http://dbkwik.webdatacommons.org | 65 |