"\uD53C\uB9AC\uBBF8\uB518 \uB300\uC0AC"@ko . "\uD53C\uB9AC\uBBF8\uB518 \uB300\uC0AC\uB294 \uD6A8\uC18C\uAC00 \uAD00\uC5EC\uD558\uB294 \uBB3C\uC9C8\uB300\uC0AC\uC774\uB2E4. DPD(Dihydropyrimidine dehydrogenase) \uD6A8\uC18C\uB294 \uD53C\uB9AC\uBBF8\uB518(pyrimidine) \uC5FC\uAE30, \uC6B0\uB77C\uC2E4 \uBC0F \uD2F0\uBBFC\uC758 \uB300\uC0AC\uC5D0 \uAD00\uC5EC\uD558\uB294 \uB9E4\uC6B0 \uC911\uC694\uD55C \uD6A8\uC18C\uB85C\uC11C \uC0DD\uCCB4\uB0B4\uC758 DNA \uBC0F RNA\uC758 \uD569\uC131\uC5D0 \uC788\uC5B4 \uC911\uC694\uD55C \uC5ED\uD560\uC744 \uD55C\uB2E4. \uC720\uC554, \uC720\uBC29\uC554 \uB4F1\uC758 \uCE58\uB8CC\uC5D0 \uC0AC\uC6A9\uB418\uB294 \uD56D\uC554\uC81C\uC778 5-FU\uB97C \uC8FC\uB85C \uB300\uC0AC\uD558\uBA70, 5-FU\uB97C \uD22C\uC5EC \uBC1B\uC740 \uD658\uC790\uC5D0\uC11C DPD \uD6A8\uC18C\uC758 \uD65C\uC131\uC5D0 \uB530\uB77C \uC2EC\uAC01\uD55C \uBD80\uC791\uC6A9\uC774 \uBC1C\uC0DD\uD560 \uC218 \uC788\uC5B4, DPD \uC720\uC804\uD615\uACFC 5-FU \uC774\uC0C1\uBC18\uC751\uACFC\uC758 \uC0C1\uAD00\uC131 \uC5F0\uAD6C\uAC00 \uB9CE\uC774 \uC9C4\uD589\uB3FC \uC654\uB2E4. \uC54C\uB780\uD1A0\uC778\uC740 \uD478\uB9B0\uACFC \uD53C\uB9AC\uBBF8\uB518 \uB300\uC0AC\uC758 \uCD5C\uC885\uC0B0\uBB3C\uB85C\uC11C \uD2B9\uC815 \uD3EC\uC720\uB958\uC640 \uBCF5\uC871\uB958 \uBC0F \uACE4\uCDA9\uC758 \uC694\uB9C9\uC561\uACFC \uC18C\uBCC0\uC5D0\uC11C \uBCFC \uC218 \uC788\uC73C\uBA70 \uC0C1\uCC98 \uCE58\uB8CC\uC5D0 \uB9CE\uC774 \uC0AC\uC6A9\uB41C\uB2E4. \uBD95\uC18C\uB294 \uD53C\uB9AC\uBBF8\uB518 \uB300\uC0AC\uC5D0 \uC788\uC5B4\uC11C \uAE30\uBCF8\uC801\uC778 \uC5ED\uD560\uC744 \uAC16\uACE0 \uC788\uB2E4\uACE0 \uAC00\uC815\uB41C\uB2E4. \uC18C\uC5D0\uC11C \uC720\uC804\uC790\uC758 \uC190\uC2E4\uC5D0 \uB530\uB77C \uC9C0\uBC29\uB300\uC0AC, \uCF5C\uB808\uC2A4\uD14C\uB864\uB300\uC0AC, \uB3C5\uC131\uC81C\uAC70, \uD53C\uB9AC\uBBF8\uB518 \uB300\uC0AC\uAC00 \uC0AC\uB78C\uACFC \uB2EC\uB9AC \uC774\uB8E8\uC5B4\uC9C4\uB2E4\uB294 \uAC83\uB3C4 \uC99D\uBA85\uB410\uB2E4. \uBD84\uB958:\uBB3C\uC9C8 \uB300\uC0AC"@ko . "\uD53C\uB9AC\uBBF8\uB518 \uB300\uC0AC\uB294 \uD6A8\uC18C\uAC00 \uAD00\uC5EC\uD558\uB294 \uBB3C\uC9C8\uB300\uC0AC\uC774\uB2E4. DPD(Dihydropyrimidine dehydrogenase) \uD6A8\uC18C\uB294 \uD53C\uB9AC\uBBF8\uB518(pyrimidine) \uC5FC\uAE30, \uC6B0\uB77C\uC2E4 \uBC0F \uD2F0\uBBFC\uC758 \uB300\uC0AC\uC5D0 \uAD00\uC5EC\uD558\uB294 \uB9E4\uC6B0 \uC911\uC694\uD55C \uD6A8\uC18C\uB85C\uC11C \uC0DD\uCCB4\uB0B4\uC758 DNA \uBC0F RNA\uC758 \uD569\uC131\uC5D0 \uC788\uC5B4 \uC911\uC694\uD55C \uC5ED\uD560\uC744 \uD55C\uB2E4. \uC720\uC554, \uC720\uBC29\uC554 \uB4F1\uC758 \uCE58\uB8CC\uC5D0 \uC0AC\uC6A9\uB418\uB294 \uD56D\uC554\uC81C\uC778 5-FU\uB97C \uC8FC\uB85C \uB300\uC0AC\uD558\uBA70, 5-FU\uB97C \uD22C\uC5EC \uBC1B\uC740 \uD658\uC790\uC5D0\uC11C DPD \uD6A8\uC18C\uC758 \uD65C\uC131\uC5D0 \uB530\uB77C \uC2EC\uAC01\uD55C \uBD80\uC791\uC6A9\uC774 \uBC1C\uC0DD\uD560 \uC218 \uC788\uC5B4, DPD \uC720\uC804\uD615\uACFC 5-FU \uC774\uC0C1\uBC18\uC751\uACFC\uC758 \uC0C1\uAD00\uC131 \uC5F0\uAD6C\uAC00 \uB9CE\uC774 \uC9C4\uD589\uB3FC \uC654\uB2E4. \uC54C\uB780\uD1A0\uC778\uC740 \uD478\uB9B0\uACFC \uD53C\uB9AC\uBBF8\uB518 \uB300\uC0AC\uC758 \uCD5C\uC885\uC0B0\uBB3C\uB85C\uC11C \uD2B9\uC815 \uD3EC\uC720\uB958\uC640 \uBCF5\uC871\uB958 \uBC0F \uACE4\uCDA9\uC758 \uC694\uB9C9\uC561\uACFC \uC18C\uBCC0\uC5D0\uC11C \uBCFC \uC218 \uC788\uC73C\uBA70 \uC0C1\uCC98 \uCE58\uB8CC\uC5D0 \uB9CE\uC774 \uC0AC\uC6A9\uB41C\uB2E4. \uBD95\uC18C\uB294 \uD53C\uB9AC\uBBF8\uB518 \uB300\uC0AC\uC5D0 \uC788\uC5B4\uC11C \uAE30\uBCF8\uC801\uC778 \uC5ED\uD560\uC744 \uAC16\uACE0 \uC788\uB2E4\uACE0 \uAC00\uC815\uB41C\uB2E4. \uC18C\uC5D0\uC11C \uC720\uC804\uC790\uC758 \uC190\uC2E4\uC5D0 \uB530\uB77C \uC9C0\uBC29\uB300\uC0AC, \uCF5C\uB808\uC2A4\uD14C\uB864\uB300\uC0AC, \uB3C5\uC131\uC81C\uAC70, \uD53C\uB9AC\uBBF8\uB518 \uB300\uC0AC\uAC00 \uC0AC\uB78C\uACFC \uB2EC\uB9AC \uC774\uB8E8\uC5B4\uC9C4\uB2E4\uB294 \uAC83\uB3C4 \uC99D\uBA85\uB410\uB2E4. \uBD84\uB958:\uBB3C\uC9C8 \uB300\uC0AC"@ko . .